Iterative 3D bayesian restoration method of SPECT volumes (OSEM-R) - Application in striatal imaging

SPECT imaging suffers from low spatial resolution and statistical noise. Consequently, the contrast of small structures is reduced, visual detection of defects is limited and exact quantification is difficult. To improve the contrast, it is possible to incorporate a blurring model into the iterative reconstruction process such as OSEM3D. This approach is well known to be effective, but time consuming. We develop a faster method to account for the spatial resolution in SPECT imaging. The purpose of this study is to compare the ability of both methods to achieve a speedy and efficient resolution recovery.